Mccabe et al. indicated that the radiolabeled agent (64Cu-DOTA-CysDb) exhibited specific targeting of CD166-positive tumors in vivo at 4 h, but the high accumulation in the liver and kidney lead to low tumor uptake (2.4 ± 0.6 %ID/g) and low tumor-to-blood ratios (2.9 ± 0.6) in BxPC-3 xenograft model [58]. This evidence concerns the gene ALCAM and neoplasm.