Consistently, in other malignancies such as cervical and prostate cancer, increased 45S levels were also described.35, 36 Previously, we found that the pro‐proliferative effects of ACA11 overexpression are ROS‐dependent 8 and the current study demonstrates the role of ROS in ribosome biosynthesis in MM cells. The gene discussed is SCARNA22; the disease is Familial prostate cancer.