Seitz et al. (2017) showed that LINC00958 was significantly upregulated in bladder cancer and exhibited phenotypic functions that showed carcinogenic characteristics. A recent study reported that HOXC13-AS was obviously upregulated in breast cancers and promoted cell proliferation by regulating the miR-497-5p/PTEN axis (Li et al., 2019b). HOXC13-AS positively affects cell proliferation and invasion by modulating the miR-383-3p/HMGA2 axis in NPC (Gao et al., 2019). The gene discussed is PTEN; the disease is breast cancer.