The DEGs enriched in insulin resistance pathway were sterol regulatory element binding transcription factor 1 (Srebf1, also known as Srebp1c), solute carrier family 27 member 1 (Slc27a1), protein kinase C, theta (Prkcq), cAMP responsive element binding protein 3-like 1 (Creb3l1), forkhead box O1 (Foxo1), TBC1 domain family, member 4 (Tbc1d4, also termed as AS160), and carnitine palmitoyltransferase 1A (Cpt1a). The gene discussed is TBC1D4; the disease is Insulin resistance.