MAPK8 and cancer: Table 1 shows the top four significant gene annotations in GO and the top five pathways in KEGG regarding the potential target of miR-193a-3p. As can be seen in Figs. 3 and 4, the KEGG pathway analysis showed that “Proteoglycans in cancer” is the most closely related pathway, while the “ErbB signaling pathway” is the second most closely related pathway. Among all the miR-193a-3p-related genes, the most enriched GO term is “protein binding”. The PPI network in Fig. 5 showed the nine genes most related to miR-193-3p, including KRAS, IGF1R, TNS1, YWHAZ, MAPK8, MDM2, BCL2L1, MAPK1, and CCND1.