TNFSF10 (TNF superfamily member 10), a cytokine that belongs to the tumor necrosis factor (TNF) ligand family,preferentially induces apoptosis in transformed and tumor cells, and TNFSF10 was significantly associated with overall survival in patients with liver cancer, breast cancer, non-small cell lung cancer and other tumors (Koç Erbaşoğlu et al., 2019; McCarthy, 2005; Piras-Straub et al., 2015). Here, TNF is linked to liver cancer.