Impaired iron homeostasis and low serum iron level due to increased absorption as well as retention of iron by reticuloendothelial cells, along with low level of erythropoietin and high level of inflammatory cytokines (IL-6) and liver hormone hepcidin, are the characteristic features of ACD [15, 26]. The gene discussed is HAMP; the disease is granular corneal dystrophy type II.