In neuroblastoma, CUX1-generated circRNA (circ-CUX1) promotes expression of enolase 1, glucose-6-phosphate isomerase, and phosphoglycerate kinase 1, and binds to EWSR1 to facilitate its interaction with MAZ, contributing to the aerobic glycolysis and neuroblastoma progression16. The gene discussed is PGK1; the disease is neuroblastoma.