We previously reported that the “set-point” for the p-CRMP2T514:CRMP2 ratio was abnormally high in lithium-responsive BD patients (compared with non-lithium-responsive BD patients as well as patients with other psychiatric and neurological disorders), but was normalized by lithium when it decreased p-CRMP2T514 levels15. Here, DPYSL2 is linked to Behcet disease.