Up to now, 16 genes have been identified that may cause USH (https://sph.uth.edu/retnet/sum-dis.htm), three genes of them (USH2A (usherin) [5], ADGRV1 (Adhesion G Protein-Coupled Receptor V1) [6] and DFNB31 (autosomal recessive deafness 31) [7]) are the USH2 genes. The gene discussed is ADGRV1; the disease is deafness.