The Prediction of Short-Term Outcome in Pregnant Women with Suspected Preeclampsia study (PROGNOSIS) demonstrated that an sFlt-1/PlGF ratio < 38 exhibited a good NPV of 99.3% to rule out PE or HELLP within 1 week and that a ratio > 38 exhibited a PPV of 36.7% to rule in PE within 4 weeks [31]. The gene discussed is PGF; the disease is preeclampsia.