TLR3 and adenocarcinoma: As a support of the relevance of NSCLC histotype to consider the TLR3 prognostic role, the in silico analysis of KM-Plotter database showed a better outcome in TLR3 expressing adenocarcinoma and no association between TLR3 expression and prognosis in squamous NSCLC, both considering stage I and stage II NSCLC patients.