Indeed, cases with an elevated percentage of tumor cells expressing caspase-3 showed concurrently a high percentage of tumor cells expressing TLR3 (>50% of total tumor cells; score 2, 3, 4); conversely, most of the cases (11/13 cases, 85%) with TLR3 low expression on tumor cells showed a concomitant low expression of caspase-3 on tumor cells (≤25% of total tumor cells; score 0, 1). The gene discussed is TLR3; the disease is neoplasm.