The combination of 5-fluorouracil and the flavonoid oroxylin from the root of a traditional Chinese medicine Scutellaria baicalensis Georgi demonstrated an increase in the population of apoptotic cells as analyzed by Annexin V-FITC/PI double staining in HepG2 human hepatocellular carcinoma cells [42]. The gene discussed is ANXA5; the disease is hepatocellular carcinoma.