CYCS and laryngeal squamous cell carcinoma: Lee et al. [38] reported the cytotoxic effects of (–)-Epigallocatechin-3-gallate (EGCG) in human laryngeal epidermoid carcinoma of the larynx Hep2 cells and found that the induction of apoptosis was accompanied by a decrease in the mitochondrial membrane potential with the release of cytochrome c from the mitochondria.