As summarized in Table 3, K-means cluster analysis with additional ANOVA identified IHC scores of vimentin (tumor center and tumor margin), E-cadherin (center and margin), claudin-1 (center and margin), Ki67 (center), ZEB1 (margin), and nuclear Snail/Slug (center and margin) as well as expression of miR-205 as factors with significant discrimination power. The gene discussed is ZEB1; the disease is neoplasm.