Next, we analyzed the expression of the two HIPK2 isoforms in a commercially available panel of first-strand cDNAs prepared from 24 human colon cancers and matched nontumor tissue and in a cohort of 26 mRNAs from randomly selected pancreatic ductal adenocarcinomas (PDAC) banked at the Regina Elena Cancer Institute. The gene discussed is HIPK2; the disease is malignant colon neoplasm.