In addition to the classic forms of LYH (lymphocytic adenohypophysitis, lymphocytic infundibulo-neurohypophysitis, lymphocytic panhypophysitis), some new forms of pituitary autoimmune disease that may cause also GHD have recently been described, namely the IgG4-related hypophysitis, the anti-CTL-4 hypophysitis and the anti-PIT-1 hypophysitis [5,6,47,48,49] (Table 1A). Here, POU1F1 is linked to hypophysitis.