Zhang et al. [49] identified that HLA-DR- CD33+ CD11b+ MDSCs from NK/T cell lymphoma patients expressed higher levels of Arg-1 and iNOS compared with the levels of MDSCs from healthy donors and strongly inhibited the CD4+ T cell proliferation but slightly suppressed CD8+ T cell proliferation. The gene discussed is CD4; the disease is T-cell non-Hodgkin lymphoma.