Retinopathy treated with laser (32 vs 11%, p = 0.003), urinary albumin/creatinine ratio >3 mg/mmol (61 vs 31%, p = 0.001), coronary arterial disease (90 vs 73%, p = 0.04) and insulin treatment (77 vs 42%, p = 0.0003) were significantly more common in patients with neuropathy. This evidence concerns the gene ALB and retinal disorder.