Interestingly, 2 (0.38%) patients had more than one concurrent LP/P germline variants, with TP53 (c.919+1G>T) and PMS2 (p.R287fs) mutations detected in a patient with luminal B tumor, and BRCA2 (p.Q1129*) and FANCI (c.158-2A>G) mutations detected in a patient with luminal A tumor. This evidence concerns the gene PMS2 and neoplasm.