LCN2 and hematologic disorder: Another study reported that the level of BM NGAL was significantly higher than that of PB NGAL in individuals with hematological malignancy, suggesting that BM NGAL would reflect the BM microenvironment better than PB NGAL.10 Hematological malignancy develops in the BM, while neutrophilic precursors as the major source of NGAL synthesis exist mostly in the BM.5 Accordingly, the accurate analysis of NGAL according to the hematological malignancy requires the measurement of BM NGAL rather than PB NGAL.10