Moreover, there is minimal control over GF presentation and delivery, which is essential for optimal cell response.18 In contrast, hyaluronic acid and heparin-based hydrogels have proven to be potent scaffolds for primary cell culture and mimic the slow, controlled release of GFs in vivo.18–27 Epidermal growth factor (EGF) plays a vital role in controlling breast tumor cell growth and differentiation. Here, EGF is linked to breast neoplasm.