In addition, CD146 was significantly associated with lower response to induction therapy in both adult and pediatric B-ALL; we partially agreed with the previous study where CD146 expression was significantly associated with higher non-CR rate, but we did not correlate its expression with CD71 and CD58; instead, we correlated it with CD34, BM blasts, CD8+, CD4+, and lymphocytes. The gene discussed is MCAM; the disease is precursor B-cell acute lymphoblastic leukemia.