SLC16A9 and gout: ALDH16A1 gene is associated with serum uric acid levels and gout, and RNA sequencing in the kidney of wild-type (WT) and Aldh16a1 knockout (KO) mice revealed changes in Slc16a9 are localized to the apical membrane of the proximal convoluted tubule cells and influence uric acid homeostasis [49].