NPPB and pulmonary arterial hypertension: There was a significant RES-mediated decrease in the PAH+RES group of the following mRNAs compared to PAH phenotype: BNP (6.7 ± 1.02 vs. 15.7 ± 1.5), Tnnc1 (0.7 ± 0.5 vs. 5.5 ± 2.7), collagen 1 (1.7 ± 0.7 vs. 2.7 ± 0.5), IL-1β (3.2 ± 0.7 vs. 4.6 ± 1.7), and an increase in IL-10 (8.7 ± 1.5 vs. 3.5 ± 1.6) (Figures 4(a)–4(e)).