UQCRC1 and neoplasm: Consistent with our in vitro findings, UQCRC1 overexpression significantly increased the tumor burden in both subcutaneous (0.49 ± 0.08 g vs. 0.79 ± 0.11 g, P < 0.05, Figure 2E-G) and orthotopic (0.48 ± 0.05 g vs. 0.90± 0.07 g, P < 0.001, Figure 2H-I) mouse models of PDAC.