We successfully established a model of hyperuricemia in rats through purine plus yeast feeding and found that the macroporous resin extract of Dendrobium candidum (DLE) could effectively reduce UA levels and improve renal function, which was assessed through kidney (CR, BUN) (Figures 2(b) and 2(c)) and liver function indicators (ALT, AST) (Figures 2(d) and 2(e)). This evidence concerns the gene GPT and hyperuricemia.