Bullatacin has been identified to be highly cytotoxic against multidrug-resistant human mammary adenocarcinoma cells; which explains the concentration-dependent cytochrome c release observed in the extract tested in this study [48–52].Nonetheless, Correa-Gordillo et al. [53] came up with a review of the antioxidant capacity of Annona muricata and categorically stated that soursop did not contain high activity or concentration of antioxidants in leaves, fresh/frozen pulp, juice as well as wine from the plant. The gene discussed is CYCS; the disease is breast adenocarcinoma.