Moreover, previous immunohistochemistry and real-time RT-PCR analyses of renal biopsies from patients with LN (n = 19) showed that CXCR3-positive cells mainly overlapped with T cells infiltrating the tubulointerstitial compartment and were rarely found in glomeruli, which supported the results reported by Segerer et al. [35]. Here, CXCR3 is linked to lobular neoplasia.