The XP-EHH results were clearer and three out of the five top peaks were directly associated with genes: CCBE1—a gene previously associated with lymphatic disease, ACTG2—an enteric smooth muscle actin gene previously associated with intestinal diseases and SUCLG2—encoding a succinate-CoA ligase, previously associated with glucose and fat metabolism. The gene discussed is CCBE1; the disease is lymphatic system disorder.