In order to identify miRNA signatures that could serve as potential biomarkers to discriminate HBC, we evaluate the expression profiles of miRNAs in HBC tumors, sporadic breast cancer (SBC), and normal breast tissues (NBT) from carriers and non-carriers of BRCA1 or BRCA2 pathogenic germline mutations using NanoString technology. The gene discussed is BRCA2; the disease is breast carcinoma.