Spindle cell/sclerosing RMS have been redefined in the WHO 2013 classification as a stand‐alone pathologic entity, distinct from ERMS.22 However, the definition criteria of SRMS are not consensual, because “spindle cells” are observed in different types of RMS‐like ERMS, RMS with VGLL2 rearrangement or with MyoD1 mutation. This evidence concerns the gene VGLL2 and embryonal rhabdomyosarcoma.