Notably, no infant had nevoid basal cell carcinoma syndrome (or Gorlin syndrome), characterized by a PTCH1 inactivating mutation.26, 27 Lastly, three SRMS sharing morphological characteristics with spindle cell sarcoma carry fusions (ie, BRAF‐SYPL1, TPM3‐NTRK, or TOP2B‐RAF1) reported in other types of MMT including infantile fibrosarcoma.28, 29, 30, 31, 32, 33, 34 The nosological status of this subgroup remained uncertain. Here, TOP2B is linked to nevoid basal cell carcinoma syndrome.