FLNA and microcephaly: Flna binds actin-nucleating Formin 2 (Fmn2) and Flna + Fmn2 null mice exhibit microcephaly, thoracoabdominal schisis, thinned ventral body wall (muscle, ribs, and sternum) and shortened gut lengths when compared to WT embryos, partially due to fewer proliferating mesenchymal cells in the sternum and ribcage [91].