Additionally, significant negative correlations were found between both markers and leptin in the group with mildly elevated lipids, between ghrelin and glucose, triglycerides and apolipoprotein A1 in the group with normal-weight hypertension, between both markers and homocysteine in both obesity-related hypertension and normal-weight hypertension. The gene discussed is LEP; the disease is obesity due to melanocortin 4 receptor deficiency.