FPR1 and type 1 diabetes mellitus: Therefore, the main objectives of this study were to: (i) Localise FPR expression in the mouse aorta, (ii) determine if the small-molecule-based FPR-agonists Cmpd17b and Cmpd43 acutely regulate vasculature tone, and (iii) whether or not Cmpd17b and Cmpd43 chronically improve endothelial function of the aorta in a model of type 1 diabetes in male mice.