However, after 6 months of WD feeding, WD mice (Figure 7E) showed significantly reduced expression of LXRβ in the ganglion cell layer (p = 0.0374), inner nuclear layer (p < 0.0001), and outer nuclear layer, as well as in the photoreceptors of the outer nuclear layer (p = 0.0020). This evidence concerns the gene NR1H2 and Wilson disease.