In line, the CD35 response was also lower in patients with subclinical CAD(1.6 [IQR 1.5–1.9]) than in patients without CAD (1.9 [IQR 1.7–2.1], p = 0.02), although the results were not statistically significant when multiple testing correction was applied (p = 0.11). This evidence concerns the gene CR1 and coronary artery disorder.