Furthermore, CD161+ Vδ1+ γδ T cell lines of IP- SSc patients produced a significantly greater amount of CCL3 (which abrogates inhibiting effects of IFNγ on fibroblast proliferation) than HC CD161+ Vδ1+ γδ T cell lines, upon TCR stimulation [104]. The gene discussed is KLRB1; the disease is systemic sclerosis.