However, in another study of JIA, 80% of CD4-CD8- of T cells were γδ T cells and γδ cells secreting IL-17 were positively correlated with innate lymphoid cells (ILC) type 3 secreting IL-17, which in turn correlated with disease severity by physician visual analogue score (VAS) [72]. The gene discussed is CD8A; the disease is juvenile idiopathic arthritis.