Furthermore, CD161+ Vδ1+ γδ T cell lines of IP- SSc patients produced a significantly greater amount of CCL3 (which abrogates inhibiting effects of IFNγ on fibroblast proliferation) than HC CD161+ Vδ1+ γδ T cell lines, upon TCR stimulation [104]. This evidence concerns the gene KLRB1 and incontinentia pigmenti.