We used the same cell lines to evaluate the FUT8 expression and found a similar pattern of overexpression of FUT8 mRNA and protein expression in cell lines that were either androgen independent (C4-2) or resistant to testosterone (DU145 and PC3) (Figure 5C,D) suggesting a positive association between FUT8 and EGFR protein expression in androgen-resistant prostate cancer cell lines. This evidence concerns the gene EGFR and Familial prostate cancer.