TP53 and neoplasm: Multivariate analysis considering age at diagnostic, tumor stage, histology, S.score based on a threshold of 0.22, which was shown to be the more predictive for prognosis (Blum et al., 2019), and mutation status in these three genes showed that the mutation status is predictive of prognosis only for TP53 and not for TERT_prom and NF2 (Fig. S11).