Our study found that the prevalence rate of fragility fractures in the diabetic population was 7.3%, which is much higher than the 5.2% in the non-T2DM population (p = 0.018, Table 1), and analyzed the association between fractures and diabetes, hypertension (HTN), HbA1c, blood lipids, BMI, level of serum 25 (OH)D3, insulin use, oral antidiabetic medication, Ccr, etc. We found that T2DM, female sex, older age, slower TUG time, and osteoporosis are risk factors for fractures. The gene discussed is INS; the disease is hypertensive disorder.