As shown in Figure 3, no heterogeneity existed for values of I2 = 0.0% and PQ = 0.744, and the combined HR value of the EFS rate was 1.73 with the corresponding 95% CI:1.39-2.07 and p < 0.05 after being merged in the six included studies, indicating that high level of Capn4 protein may lead to an inferior EFS in cancer patients. Here, CAPNS1 is linked to cancer.