AKT1 and gastric cancer: A study reported that miR-34a, which was weakly expressed in GC tissues, attenuated the malignant behavior of GC cells by directly targeting PDGFR and MET expression and subsequently regulating the phosphorylation of Akt through PI3K/Akt/mTOR pathway (Peng et al., 2014; Wei et al., 2015).