This patient had a high percentage of Tim-3 + CD3+, Tim-3 + CD244 + CD4+, Tim-3 + CD57 + CD4+, Tim-3 + CD8+, Tim-3 + CD244 + CD8+, and PD-1 + Tim-3 + CD4+ T cells in the BM compared with other AML samples; however, there was no evident difference in PB. The gene discussed is CD8A; the disease is acute myeloid leukemia.