IL‐17A is genetically associated with Staphylococcal infections, and data from skin and acute S. aureus infection mouse models support a protective role for IL‐17.25, 26, 27, 28, 29 While systemic levels of IL‐17A can serve as a biomarker of chronic S. aureus tissue infection, antibody‐mediated blockade of IL‐17 1 week after haematogenous seeding of tissues did not indicate a mechanistic role for IL‐17A in driving bacterial persistence in infected foci between 2 and 4 weeks of infection (data not shown). This evidence concerns the gene IL17A and infection.