The expression of skeletal muscle autophagy-related genes (ATG14, RB1CC1/FIP200, GABARAPL1, SQSTM1/p62 and WIPI1) and proteins (LC3BII, SQSTM1/p62 and ATG5) were also significantly decreased in type 2 diabetic patients [72], and skeletal muscle autophagy was decreased. The gene discussed is SQSTM1; the disease is type 2 diabetes mellitus.