Almost half of recurrent IDHWT tumours (43%; 3/7) harboured at least one potentially actionable variation in the genes EGFR (14%; 1/7), PTEN (14%; 1/7), BRCA1 (14%; 1/7), BRCA2 (14%; 1/7), and ATM (14%; 1/7; Figure 2 and Table 4). This evidence concerns the gene PTEN and neoplasm.