TP53 and colorectal cancer: In colorectal cancer, it has been reported that several lncRNAs can directly bind to proteins or act as miRNA sponges to participate in cellular signaling pathways such as β-catenin, p53, JAK/STAT, AKT/mTOR, and NF-κB, among others, thereby affecting cell cycle progression and/or EMT (epithelial mesenchymal transition) to control tumor cell growth, migration, and invasion (Kawasaki et al., 2016; Yang et al., 2017; Jiang et al., 2018; Wang et al., 2018; Sun et al., 2018; Tang et al., 2019).