Rendtlew Danielsen et al. (44) analyzed the expression of CD47 and TSP-1 and TSP-2 in plasmocytes from MM patients using fluorescence-activated cell sorting and found that CD47 and TSP-1 and TSP-2 ligands are highly up-regulated in the MM interstitial environment. The gene discussed is THBS1; the disease is Miyoshi myopathy.