Menin is correlated with poor prognosis and NE lung cancer in order to elucidate whether menin expression correlates with NE differentiation in human NSCLC specimens, we randomly collected human primary lung cancer specimens, including histologically classified specimens from 157 cases of NSCLC and 34 cases of SCLC (Supplementary Table 1), and performed menin IHC staining. This evidence concerns the gene MEN1 and lung cancer.