Because CCL5 is overexpressed in ccRCC and is related to poor prognosis, we next conducted functional experiments to explore the potential biological function of CCL5. First of all, we used small interfering RNAs to lower expression levels of CCL5 in the renal cell carcinoma cell line 769-P (Figure 9C) and evaluated the cell proliferation ability by Cell Counting Kit-8 (CCK-8). Here, CCL5 is linked to hereditary clear cell renal cell carcinoma.